Synthesis, structure and in vitro biological evaluation of new lupane and dammarane triterpenoids fused with pyrazine heterocycle

Autor:	A. D. Zorina, Vladimir V. Zarubaev, Evgenii I. Rodionov, Rostislav E. Trifonov, Alina A. Rodionova, Galina L. Starova, Arif R. Mehtiev, Stanislav I. Selivanov, Nadezhda S. Nikiforova, Sergei A. Marchenko
Rok vydání:	2019
Předmět:	chemistry.chemical_classification Pyrazine 010405 organic chemistry Stereochemistry Dammarane General Chemistry 010402 general chemistry 01 natural sciences In vitro 0104 chemical sciences chemistry.chemical_compound Triterpenoid chemistry Lactone Biological evaluation
Zdroj:	Mendeleev Communications. 29:500-502
ISSN:	0959-9436
DOI:	10.1016/j.mencom.2019.09.007
Popis:	Derivatives of natural lupenone, dipterocarpol, alnincanone and semisynthetic dipterocarpol lactone fused with pyrazine heterocycle along C2–C3 positions were obtained by the Willgerodt–Kindler reaction, X-ray analysis having been used for the structure identification. Anti-influenza and anti-proliferative activities of the compounds obtained were estimated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::48749b6474c60053b388e822990a6c65 https://doi.org/10.1016/j.mencom.2019.09.007 Zobrazit plný text záznamu Full Text from ScienceDirect