Iron-Mediated Total Synthesis of 2,7-Dioxygenated Carbazole Alkaloids

Autor:	Arndt W. Schmidt, Hans-Joachim Knölker, Micha P. Krahl, Olga Kataeva
Rok vydání:	2012
Předmět:	Clausine O chemistry.chemical_classification chemistry.chemical_compound Chemistry Carbazole Organic Chemistry Salt (chemistry) Total synthesis Organic chemistry Clausine H Physical and Theoretical Chemistry
Zdroj:	European Journal of Organic Chemistry. 2013:59-64
ISSN:	1434-193X
Popis:	We describe the efficient iron-mediated total synthesis of clausine O, clausine H (clauszoline-C) and anti-HIV active 7-methoxy-O-methylmukonal and clausine K (clauszoline-J). Consecutive C–C and C–N bond formations between 3-methoxy-4-methylaniline and a cyclohexadienyliumiron complex salt afforded 2,7-dimethoxy-3-methylcarbazole, which served as common intermediate en route to the four alkaloids.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::486b695b5e6c51e00f38dd850ae60dce https://doi.org/10.1002/ejoc.201201251 Zobrazit plný text záznamu Plný text