An Environmentally Benign Water Promoted Catalyst Free Highly Efficient, One-pot Synthesis of 2-Imino-4-thiazolidinone

Autor: Tulshiram L. Dadmal, Ravindra M. Kumbhare, Balasubramanian Sridhar, Umesh B. Kosurkar
Rok vydání: 2014
Předmět:
Zdroj: Journal of Heterocyclic Chemistry. 51:1522-1527
ISSN: 0022-152X
Popis: A practical and efficient protocol has been developed for the synthesis of 2-imino-4-thiazolidinone through a unique one pot three-component reaction of variety of amines, isothiocyanate and ethylbromoacetate in water. The method is free of catalyst and other toxic solvents, has shorter reaction times, high-yielding, effortlessness in isolation of product, making it more eco-friendly process, and suitable for large scale operation.
Databáze: OpenAIRE
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