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Background: ASB is a common problem in pregnant women. About 40% of women with untreated asymptomatic bacteriuria during pregnancy develop pyelonephritis, this has the possibility of leading to low birth weight, preterm, premature rupture of membranes and preterm labour. This study is aimed to assess the prevalence of asymptomatic bacteriuria and antimicrobial susceptibility pattern isolating among pregnant women attending the antenatal clinical care of Assosa General Hospital in western Ethiopia.Methods: A facility-based cross-sectional study was conducted from January to February 2019. Well-mixed and uncentrifuged urine specimens obtained from the pregnant women were directly inoculated on cystine lactose electrolyte deficient agar (CLED) (Oxoid, Ltd, England) media by streak plate method. Bacterial isolates were identified as per the standard bacteriological procedure using colony characteristics, gram-staining, and series of biochemical tests. Antimicrobial susceptibility test was carried out by Kirby- Bauer disk diffusion technique on Muller-Hinton agar medium and the diameter of zone of inhibition was interpreted according to Clinical Laboratory Standard Institute (CLSI) guidelinesResult: The overall prevalence of ASB among pregnant women in this study was 14.85%. E-coli was the most predominant isolate (50 %,) followed by K. pneumoniae (16.7%,), S. aureus (14.3%), coagulase-negative staphylococci (CONS) (11.9%), and group B streptococci (GBS) (7.1%). Gram-negative bacteria were highly resistant for tetracycline (96.4%), ampicillin. Gram-positive bacteria were 100% sensitive for ceftazidime. Conclusion: Significant bacteriuria was observed in asymptomatic pregnant women. Therefore, routine laboratory diagnosis of ASB in pregnant women in addition to providing appropriate treatment should be needed to reduce its complications. |
