Synthesis of 4-O-β-D-Glucopyranosyl-L-rhamnopyranose

Autor:	G. M. Bebault, G. G. S. Dutton
Rok vydání:	1972
Předmět:	chemistry.chemical_compound Chemistry Bromide Yield (chemistry) Organic Chemistry Condensation Scillabiose General Chemistry Medicinal chemistry Catalysis
Zdroj:	Canadian Journal of Chemistry. 50:3373-3378
ISSN:	1480-3291 0008-4042
DOI:	10.1139/v72-539
Popis:	4-O-(β-D-Glucopyranosyl)-L-rhamnose (scillabiose) has been synthesized in 55% yield by condensation of 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide with methyl 2,3-O-isopropylidene-α-L-rhamnopyranoside using mercuric cyanide in acetonitrile (Helferich reaction). The disaccharide and the derived alditol are both syrups but each forms a crystalline peracetate. A convenient synthesis of 1-deoxy-D-erythritol is described.
Databáze:	OpenAIRE
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