| Autor: |
M. Cecchi, Jack W Silcox, J.M. Scott, K.D. Brighton, Suzanne Hendrix, Bruce L. Brown, D. Hedges |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
The Journal of Prevention of Alzheimer's Disease. :1-4 |
| ISSN: |
2274-5807 |
| DOI: |
10.14283/jpad.2015.79 |
| Popis: |
Event-related potentials (ERPs) are a physiological measure of cognitive function that have shown diagnostic and prognostic utility in Alzheimer’s disease (AD). In this study, we used a novel eigenvector-based technique to better understand brain electrophysiological differences between subjects with mild AD and healthy controls (HC). Using ERPs from 75 subjects with mild AD and 95 HC, we first calculated cognitive task eigenvectors within each subject from three conditions and then calculated second-order eigenvector components to compare the AD group to the HC group. A MANOVA of the three second-level components discriminated between AD and HC multivariately (Wilks’ lambda=.4297, p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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