Non-aqueous capillary electrophoretic separation and detection of 6H-pyrimido[2,1-a]isoindoles

Autor:	Karel Nesměrák, Veronika Horká, Martin Pumera
Rok vydání:	2002
Předmět:	Aqueous solution Chromatography Isoindoles Chemistry Capillary action Analytical chemistry Filtration and Separation Analytical Chemistry Electrophoresis chemistry.chemical_compound Capillary electrophoresis Lactam Uv detection Acetonitrile
Zdroj:	Journal of Separation Science. 25:443-446
ISSN:	1615-9314 1615-9306
Popis:	A non-aqueous capillary electrophoresis system for separating and detecting antidepressant drugs based on the coupling of capillary electrophoresis separation in acetonitrile and UV detection is described. The system offers a rapid simultaneous measurement in less than 12 min for six priority pyrimidoisoindoles. These antidepressants were detected down to the 2.5 × 10 -6 -4.2 x 10 -6 mol/L level, with linearity up to the 1 x 10 -3 mol/L level examined. A highly stable response was observed for repetitive injections (R.S.D. < 2.6%, n=12). The influence of pH and content of acetonitrile upon the electrophoretic mobilities was also studied.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::47e74705568d26f73165d4e26e617126 https://doi.org/10.1002/1615-9314(20020501)25:7<443::aid-jssc443>3.0.co Zobrazit plný text záznamu Plný text