Biosynthesis of anacardic acids from acetate inGinkgo biloba

Autor:	Joanne L. Gellerman, Hermann Schlenk, Wayne H. Anderson
Rok vydání:	1974
Předmět:	Chemistry Decarboxylation Stereochemistry Organic Chemistry Short-chain fatty acid Cell Biology Shikimic acid Ring (chemistry) Biochemistry Anacardic acids chemistry.chemical_compound Polyketide Biosynthesis Organic chemistry Chemical decomposition
Zdroj:	Lipids. 9:722-725
ISSN:	1558-9307 0024-4201
DOI:	10.1007/bf02532182
Popis:	Anacardic acids synthesized from [1-14C] and [2-14C] acetates byGinkgo biloba were subjected to chemical degradation to locate the14C in the molecules. Radioactivity in the carboxyl group was determined by decarboxylation and counting the resulting CO2; in the aliphatic chian, by oxidation of anacardol from which three homologous fatty acids are obtained; and in ring C-6, chain C-1 and chain C-2 by decarboxylation of these fatty acids where the carboxyl groups represent these respective C atoms. Distribution of14C in the anacardic acids indicates that synthesis of the chain and of the ring are separate processes. According to its radioactivity, ring C-6 originates from the chain. A polyketide mechanism appears likely for the ring synthesis, although considerable randomization of 1-14C and of 2-14C from the acetates had occurred in the plants.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::47d4e4f49a6bd0ac669444099f32ab28 https://doi.org/10.1007/bf02532182 Zobrazit plný text záznamu Full text from SpringerLink Plný text