ChemInform Abstract: Modification of Nucleic Acids Using [3 + 2]-Dipolar Cycloaddition of Azides and Alkynes

Autor:	Timofei S. Zatsepin, Alexey V. Ustinov, Vladimir A. Korshun, Irina A. Stepanova, Veronika V. Dubnyakova, Elena V. Nozhevnikova
Rok vydání:	2010
Předmět:	chemistry.chemical_classification chemistry.chemical_compound chemistry Nucleic acid Alkyne General Medicine Azide Combinatorial chemistry Cycloaddition DNA Conjugate
Zdroj:	ChemInform. 41
ISSN:	0931-7597
DOI:	10.1002/chin.201052236
Popis:	The use of azide and alkyne cycloaddition reaction in the synthesis of conjugates of nucleic acids and oligodeoxyribonucleotides is reviewed. Data on the chemical and enzymatic methods for introducing azides and alkynes into DNA are summarized.
Databáze:	OpenAIRE
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