Suspected Ofloxacin-Induced Seizures in an Elderly Patient

Autor:	Deborah S Anderson, Carlos W Tam, Augustine S Aruna
Rok vydání:	1997
Předmět:	Intravenous dose business.industry Anesthesia Pharmaceutical Science Medicine Ofloxacin business Elderly patient medicine.drug
Zdroj:	Journal of Pharmacy Technology. 13:174-176
ISSN:	1549-4810 8755-1225
DOI:	10.1177/875512259701300407
Popis:	Objective: To report a case of probable ofloxacin-induced seizures. Case Summary: A 74-year-old white man received a single intravenous dose of ofloxacin administered over a 60-minute period. Approximately 4 hours later, he developed seizure-like tremors in all extremities, fecal incontinence, and shortness of breath with harsh, labored breathing. Ofloxacin was discontinued, and the seizure-like tremors subsided within 4 hours of onset. Discussion: The time course of events suggested that ofloxacin was the cause of a suspected seizure in this patient. Other causes of seizure were ruled out. Seizures have been reported in less than 1% of patients receiving ofloxacin. Conclusions: Ofloxacin can cause seizures, and healthcare providers should be aware of the potential for this adverse effect.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::47c9a3c3dc88326e41f98a49baabab94 https://doi.org/10.1177/875512259701300407 Zobrazit plný text záznamu