Detection of Urea and Ammonia with Aluminium Coated Polysilicon Nanoresonators
| Autor: | Chinnamani Mottour Vinayagam, Anju Chadha, S. Gayathri, Enakshi Bhattacharya, Fidal Vallam Thodi |
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| Rok vydání: | 2019 |
| Předmět: |
0303 health sciences
Urease biology Chemistry chemistry.chemical_element 02 engineering and technology Ammonia volatilization from urea 021001 nanoscience & nanotechnology Ascorbic acid 03 medical and health sciences Ammonia chemistry.chemical_compound Ammonium hydroxide Etching (microfabrication) Aluminium biology.protein Urea 0210 nano-technology 030304 developmental biology Nuclear chemistry |
| Zdroj: | 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII). |
| DOI: | 10.1109/transducers.2019.8808398 |
| Popis: | Aluminium coated polysilicon (Al-polySi) nanoresonator has been used to design a urea biosensor. The etching characteristic of Al by the ammonium hydroxide from urea hydrolysis in the presence of urease was used to estimate the urea concentration. Urease immobilized on Al coated polySi indicated smoothening of the surface with increasing urea concentration, confirming the etching of Al. The nanoresonator could estimate between 10-1000 nM concentrations of urea. The sensing was not affected in the presence of interferents such as uric acid and ascorbic acid, thus making it specific for urea. The sensor was found to be highly sensitive and specific and can have potential application in the field of medical diagnostics and environmental monitoring. |
| Databáze: | OpenAIRE |
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