Immunological abnormalities in opsoclonus cerebellopathy
| Autor: | O. Kuperman, Y. Herishanu, R. Apte |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Cerebellum
T suppressor Pathology medicine.medical_specialty business.industry medicine.medical_treatment Opsoclonus medicine.disease law.invention Ophthalmology medicine.anatomical_structure Steroid therapy Autoimmune Process law Immunology medicine Adenocarcinoma Suppressor Neurology (clinical) business Mastectomy |
| Zdroj: | Neuro-Ophthalmology. 5:271-275 |
| ISSN: | 1744-506X 0165-8107 |
| DOI: | 10.3109/01658108509004941 |
| Popis: | Opsoclonus and other cerebellar symptomatology developed in a patient who underwent mastectomy for adenocarcinoma of the breast. No evidence for metastases was found. Immunological studies demonstrated decreased function of T suppressor cells and hyperreactivity of T helper cells in spite of a normal suppressor/ helper ratio. The clinical condition, as well as the immunological abnormalities normalized under steroid treatment. An autoimmune process as etiopathogenesis of this paraneoplastic syndrome is proposed. |
| Databáze: | OpenAIRE |
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