Quantitative ischemia detection during cardiac MR stress testing
| Autor: | J.A. Derbyshire, Bernhard Gerber, David A. Bluemke, Nael F. Osman, Smita Sampath, Dara L. Kraitchman, Jerry L. Prince |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Stress testing Ischemia Magnetic resonance imaging medicine.disease medicine.anatomical_structure Coronary occlusion Internal medicine Occlusion medicine Cardiology cardiovascular diseases Radiology business Electrocardiography HARP Artery |
| Zdroj: | 2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society. |
| DOI: | 10.1109/iembs.2001.1017313 |
| Popis: | Because ECG alterations due to ischemia cannot be reliably detected in the high-field MRI environment, detection of wall motion abnormalities are often the only method to ensure patient safety. In this study, we investigate the use of real-time Harmonic Phase (HARP) MRI for the quantitative, operator-independent detection of the onset of ischemia during acute coronary occlusion. Six mongrel dogs underwent acute coronary artery ischemia of 2 minutes' duration while continuous HARP MR images were acquired followed by 5 minutes of reperfusion. During a second ischemic episode, conventional cine wall motion images were acquired. The time from occlusion to the detection of ischemia by each MR technique, as well as ECG ischemic alterations, was determined. In 5 of 6 animals, the onset of ischemia was detected significantly earlier by HARP than by cine MRI (11 /spl plusmn/ 5 s HARP vs. 34 /spl plusmn/ 14.8 s cine, P |
| Databáze: | OpenAIRE |
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