The use of tuftsin in experimental leprosy

Autor:	Urliapova Ng, Freĭdlin Is, Anokhina Vv, Iushchenko Aa, Iushin MIu, Eskina Im, Vishnevetskiĭ Rf, Vishnevetskiĭ Fe
Rok vydání:	1991
Předmět:	Tuftsin General Medicine Biology medicine.disease General Biochemistry Genetics and Molecular Biology In vitro chemistry.chemical_compound chemistry Cell culture In vivo Immunology medicine Cba mice Leprosy
Zdroj:	Bulletin of Experimental Biology and Medicine. 112:1152-1156
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf00839564
Popis:	The effect of tuftsin was studied in vivo using CBA mice infected with M. leprae by Shepard's technique and in vitro using macrophage-like cell line P. 388 (Co-cultivated with M. leprae) and the cultivated leproma tissue. It was found out that tuftsin acted as a stimulator of M. leprae multiplication in foot-pads of mice and as a prolongator of M. leprae survival in the cells of macrophage-like cell line P .388. It is concluded that using tuftsin might be useful in view of studying different aspects of experimental leprosy.
Databáze:	OpenAIRE
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