Synthesis of 5-substituted 2-ylidene-1,3-thiazolidin-4-one derivatives and evaluation of their anticancer and antioxidant activities

Autor:	Salwa S. Abdelwahab, Osama M. Ahmed, Khaled F. Saied, Kamal A. Kandeel
Rok vydání:	2019
Předmět:	Antioxidant 010405 organic chemistry Phenyl isothiocyanate medicine.medical_treatment Organic Chemistry Ketene Transesterification 010402 general chemistry 01 natural sciences 0104 chemical sciences chemistry.chemical_compound chemistry Ethyl cyanoacetate medicine Organic chemistry Malononitrile
Zdroj:	Chemistry of Heterocyclic Compounds. 55:993-1003
ISSN:	1573-8353 0009-3122
DOI:	10.1007/s10593-019-02568-5
Popis:	Novel 5-(aroyl)methyl- and 5-(aroyl)methylen-2-ylidene-1,3-thiazolidin-4-ones have been prepared in high yields using ketene N,S-acetal salts, obtained from phenyl isothiocyanate and propanedinitrile or ethyl cyanoacetate. Several of the newly synthesized 1,3-thiazolidin-4-one derivatives demonstrate high antioxidant and anticancer activities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::479a95f11d6b9511f8dde6c87ae64c36 https://doi.org/10.1007/s10593-019-02568-5 Zobrazit plný text záznamu Full text from SpringerLink