Separation of Isomeric Metabolites and Gangliosides with High Performance (Drift Tube) Ion Mobility–Mass Spectrometry

Autor:	Julia L. Kaszycki, Claire Dauly, Anas Kamleh
Rok vydání:	2022
Předmět:	Analytical Chemistry
Zdroj:	LCGC North America. :7-12
ISSN:	1939-1889 1527-5949
DOI:	10.56530/lcgc.na.jw1886w1
Popis:	The study of metabolites and gangliosides is increasingly important in drug discovery (1) and immunology (2). Accurate analysis of biologically relevant isomers is important because their structure affects their molecular properties. Typically, the isomers are separated using chromatography prior to mass spectrometry (MS) analysis. However, specialized chromatographic methods that distinguish isomers frequently require a complex setup and long runs. Techniques that allow accurate results to be acquired quickly and efficiently would be beneficial.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4799f73ca76ffc95e660fed20c5958c3 https://doi.org/10.56530/lcgc.na.jw1886w1 Zobrazit plný text záznamu