C-terminal glyoxylyl peptides for sensitive enzyme-linked immunosorbent assays

Autor:	Florence Urbès, Jean-Sébastien Fruchart, Hélène Gras-Masse, Oleg Melnyk
Rok vydání:	2001
Předmět:	chemistry.chemical_classification Pharmacology toxicology Bioengineering Hydrazide Biochemistry Molecular biology Peptide antigen Analytical Chemistry chemistry.chemical_compound Enzyme chemistry Drug Discovery Molecular Medicine Linker
Zdroj:	Letters in Peptide Science. 8:253-258
ISSN:	1573-3904 0929-5666
DOI:	10.1007/bf02446525
Popis:	A model peptide antigen derived from HCV Coreprotein was modified by a hydrophilic glyoxylamide arm using atartaramide-based linker and used in an enzyme-linkedimmunosorbent assay (ELISA) on hydrazide plates. A comparativestudy with the standard non-covalent adsorption proceduresdemonstrated a large gain in sensitivity for the detection ofantibodies in HCV-positive sera.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::476b72fe84c3bbfe9f9ea71f84280489 https://doi.org/10.1007/bf02446525 Zobrazit plný text záznamu Full text from SpringerLink