Isolation, characterization and structural elucidation of the leaves of Amischophacelus axillaris and Canthium dicoccum

Autor: K. S. Meghashree, Guddapa Halligudra, N. Ashok Kumar, K. P. Latha, M.S. Sarvajith, A. Subbaraju, H. M. Vagdevi
Rok vydání: 2022
Předmět:
Zdroj: Materials Today: Proceedings. 54:566-574
ISSN: 2214-7853
DOI: 10.1016/j.matpr.2021.09.067
Popis: Amischophacelus axillaris belongs to the family of Commelinaceae and Canthium dicoccum belongs to the family of Rubiaceae, Literature survey emphasised that, these plants are reported for wide variety of uses in traditional medicine. The local healers are using A. axillaris (L.) and C. dicoccum (Gaertn.) Merr. to cure several diseases. This encouraged us to isolate bioactive compounds from the leaves of these two medicinal plants. Leaves portions of Amischophacelus axillaris and Canthium dicoccum were treated with different solvents such as pet-ether, ethylacetate and ethanol. The solvents from all the extracts were vaporized under condensed pressure using rotavapour to get compounds. TLC of ethylacetate leaves extract of A. axillaris and C. dicoccum was carried out to select appropriate mobile phase to achieve reasonably good separation in column chromatography. A. axillaris showed good separation of varying proportion mixture of pet-ether and ethylacetate in the ratio of 00:100 and ethanol extract of C. dicoccum showed good separation of varying proportion mixture of acetone and methanol in the ratio of 50:50.The structure of this compound 7-hydroxy-2H-chromen-2-one and 8-hydroxy-6,7-dimethoxy-2H-chromen-2-one was characterized as by means of 1H NMR, 13C NMR, IR and MS spectral data.
Databáze: OpenAIRE