Efficient image analysis for large-scale next generation histopathology using pAPRica

Autor: Jules Scholler, Joel Jonsson, Tomás Jordá-Siquier, Ivana Gantar, Laura Batti, Bevan L. Cheeseman, Stéphane Pagès, Ivo F. Sbalzarini, Christophe M. Lamy
Rok vydání: 2023
Popis: The large size of imaging datasets generated by next-generation histology methods limits the adoption of those approaches in research and the clinic. We propose pAPRica (pipelines for Adaptive Particle Representation image compositing and analysis), a framework based on the Adaptive Particle Representation (APR) to enable efficient analysis of large microscopy datasets, scalable up to petascale on a regular workstation. pAPRica includes stitching, merging, segmentation, registration, and mapping to an atlas as well as visualization of the large 3D image data, achieving 100+ fold speedup in computation and commensurate data-size reduction.
Databáze: OpenAIRE