A dinuclear silver compound with 5,6,7-trimethyl-[1,2,4]triazolo[1,5-a]pyrimidine with a short Ag–Ag bond. Synthesis, characterization, single-crystal structure analysis and cytostatic activity
| Autor: | Urho Turpeinen, Gerard A. van Albada, Koen Bavelaar, Mirte Kraaijkamp, Patricia Marqués-Gallego, Ramzi Khalil, Ilpo Mutikainen, Jaap G. Haasnoot, Jan Reedijk |
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| Rok vydání: | 2011 |
| Předmět: |
chemistry.chemical_classification
Denticity Pyrimidine 010405 organic chemistry Chemistry Ligand Stereochemistry Crystal structure 010402 general chemistry 01 natural sciences 0104 chemical sciences Coordination complex Ion Inorganic Chemistry Crystallography chemistry.chemical_compound Materials Chemistry Chelation Physical and Theoretical Chemistry Single crystal |
| Zdroj: | Inorganica Chimica Acta. 366:81-84 |
| ISSN: | 0020-1693 |
| DOI: | 10.1016/j.ica.2010.10.014 |
| Popis: | A new dinuclear coordination compound with the ligand 5,6,7-trimethyl[1,2,4]triazolo[1,5-a]pyrimidine (abbreviated as tmtp) is described, together with its 3D crystal structures and spectroscopic properties. The compound shows a high cytostatic activity in ovarian cancer cell lines. The solid state structure of the compound is dinuclear based, in which the ligand tmtp uses two nitrogens (N3 and N4) to chelate to two different Ag(I) ions. The Ag–Ag distance is relatively short (3.109 A), but is considered as too long for M–M bonding. The Ag(I) coordination is completed by weakly coordinated, asymmetric bidentate nitrate anions (Ag–O = 2.481–2.819 A). |
| Databáze: | OpenAIRE |
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