Electron microscopical analysis of meiotic chromosomes from human spermatocytes during and after treatment with steroid hormones

Autor: Jørgen G. Berthelsen, Marie Føgh, Niels E. Skakkebæk
Rok vydání: 1980
Předmět:
Zdroj: Carlsberg Research Communications. 45:9-23
ISSN: 0105-1938
DOI: 10.1007/bf02906527
Popis: The effect of steroid hormones on the ultrastructure of meiosis in the human male was analyzed by three dimensional reconstruction of 460 chromosomes from 7 early pachytene, 2 mid pachytene and 1 late pachytene spermatocyte nuclei. The testicular biopsy was obtained from a volunteer who had been treated with d-norgestrel 500 mcg per day orally and testosterone enanthate 200 mg every 4 weeks intramuscularly for 8 months and who was still under treatment. The volunteer had 17 months previously been treated with cyproterone acetate 5 mg per day orally for 6 months.
Databáze: OpenAIRE