Electron microscopical analysis of meiotic chromosomes from human spermatocytes during and after treatment with steroid hormones
Autor: | Jørgen G. Berthelsen, Marie Føgh, Niels E. Skakkebæk |
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Rok vydání: | 1980 |
Předmět: |
medicine.medical_specialty
medicine.medical_treatment Cyproterone acetate General Medicine Spermatocyte Biology Biochemistry Steroid chemistry.chemical_compound Synaptonemal complex medicine.anatomical_structure Endocrinology Meiosis chemistry Internal medicine medicine Volunteer Testosterone Hormone |
Zdroj: | Carlsberg Research Communications. 45:9-23 |
ISSN: | 0105-1938 |
DOI: | 10.1007/bf02906527 |
Popis: | The effect of steroid hormones on the ultrastructure of meiosis in the human male was analyzed by three dimensional reconstruction of 460 chromosomes from 7 early pachytene, 2 mid pachytene and 1 late pachytene spermatocyte nuclei. The testicular biopsy was obtained from a volunteer who had been treated with d-norgestrel 500 mcg per day orally and testosterone enanthate 200 mg every 4 weeks intramuscularly for 8 months and who was still under treatment. The volunteer had 17 months previously been treated with cyproterone acetate 5 mg per day orally for 6 months. |
Databáze: | OpenAIRE |
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