Trombolisis intravenosa en accidente cerebro vascular isquémico agudo en un hospital público de Chile: Análisis prospectivo de 54 casos
| Autor: | Isabel Navarrete, Juan Monsalve, Felipe Aravena, Marcelo Morales, Elena Nieto, Sheila Caba, Hugo Lara, Carlos Guevara O, Kateryna Bulatova |
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| Rok vydání: | 2016 |
| Předmět: |
Intracerebral hemorrhage
business.industry Mortality rate medicine.medical_treatment General Medicine Thrombolysis medicine.disease 03 medical and health sciences 0302 clinical medicine Modified Rankin Scale Anesthesia Severity of illness Ischemic stroke medicine 030212 general & internal medicine Prospective cohort study business Stroke 030217 neurology & neurosurgery |
| Zdroj: | Revista médica de Chile. 144:434-441 |
| ISSN: | 0034-9887 |
| DOI: | 10.4067/s0034-98872016000400004 |
| Popis: | Background Intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) reduces disability in patients with ischemic stroke. However, its implementation in Chilean public general hospitals has been slow and faces some difficulties. Aim To analyze the results of an intravenous thrombolysis protocol implementation in a public general hospital. Material and methods During a lapse of 28 months a standardized protocol for intravenous thrombolysis implemented in the emergency room of a public hospital, was prospectively evaluated. Fifty four patients with ischemic stroke were treated and assessed three months later as outpatients. Results At three months of follow-up, 66.4% of patients subjected to thrombolysis had a favorable evolution, defined as having 0 to 1 points in the modified Rankin scale. Intracerebral hemorrhage rate was 11.1%, including 5.5% of symptomatic intracerebral hemorrhage. Four percent of patients had systemic bleeding complications after thrombolysis. The mortality rate was 14.8%. Conclusions The success rates, mortality, and complications rate were comparable to the results obtained in international studies, despite of the absence of a stroke unit to manage stroke and its complications. |
| Databáze: | OpenAIRE |
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