| Autor: |
Thierry Christiaens, Monique Elseviers, Jan De Maeseneer, An De Sutter, Mieke L van Driel, Robert Vander Stichele |
| Rok vydání: |
2008 |
| Předmět: |
|
| Zdroj: |
Pharmacoepidemiology and Drug Safety. 17:1113-1122 |
| ISSN: |
1053-8569 |
| Popis: |
Purpose: To explore the effect on prescribing of policies that lift reimbursement restrictions on selected H2-antihistamines and proton pump inhibitors (PPI) and of practice recommendations. Methods: Monthly claims based data for proton pump inhibitors (PPIs) and H-antihistamines were obtained from the national health insurance database (Farmanet 1997-2005). Two policies were issued. In March 2001 two H2-antihistamines and in March 2003 two PPIs became available without restrictions. An evidence report was distributed in September 2004. Periods before and after implementation of the interventions were compared. Interrupted time series with segmented regression analysis was used to assess and compare time trends. Results: The first policy resulted in an increase of volume (1.6 million DDDs; 95% CI 1.4-1.8 million; p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Plný text