Déficit de proteína C en un paciente con coagulación intravascular diseminada asociada a sepsis y trombosis venosa profunda
| Autor: | Pablo Llarena, Germán Kaltenbach, Mauro Tassin, Federico Laffaye |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Clotting factor
medicine.medical_specialty business.industry medicine.disease Gastroenterology Surgery Sepsis Purpura Venous thrombosis Coagulation Protein C deficiency hemic and lymphatic diseases Internal medicine Pediatrics Perinatology and Child Health medicine Platelet medicine.symptom business circulatory and respiratory physiology Purpura fulminans |
| Zdroj: | Archivos Argentinos de Pediatria. 111:e28-e30 |
| ISSN: | 0325-0075 |
| DOI: | 10.5546/aap.2013.e28 |
| Popis: | Disseminate intravascular coagulation (DIC) is a clinical pathological syndrome associated to several diseases. Sepsis is the most common cause in infants and children. DIC results from the anomalous activation of blood coagulation, widespread formation of thrombi in the microcirculation, and consumption of clotting factors and platelets. Clinical findings are variable; the most common is bleeding, followed by purpura and acral gangrene (purpura fulminans). We report a patient with sepsis associated-DIC and concurrent deep venous thrombosis. The diagnostic evaluation allowed to discover inherited thrombophilia associated to protein C deficiency. |
| Databáze: | OpenAIRE |
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