| Popis: |
This chapter introduces the story of pig genome mapping and sequencing. It presents the heterogeneous interests and activities of a small and tight-knit community, in which maps, sequencing data, resources and tools were developed for—and immediately linked to—the problems of pig breeding and transplantation biology. A community of pig genomicists converged in mapping projects that took place from the early-1990s onwards. In these initiatives, they characterised the positions of genes and genetic markers on chromosomes with a view to this information being deployed in agriculture and biomedicine. This community was intimately involved in most aspects of the creation of a reference genome, either directly or by guiding the focus of the Sanger Institute, the institution that was contracted to undertake the sequence determination. The Sanger Institute therefore had a different role in pig genomics than in yeast and human genomics. This distinct role was deeply conditioned by the historical trajectory of the pig genetics community. |
