ChemInform Abstract: Terpenoids. Part 72. Iodoxybenzene Oxidation of 1-Naphthols: Synthesis of Mansonone A
| Autor: | D Murali, Krishna Gs Rao |
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| Rok vydání: | 1988 |
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| Zdroj: | ChemInform. 19 |
| ISSN: | 0931-7597 |
| Popis: | Substituted 1-naphthols I $(R_1-R_4=H$; $R_1=Me, R_2-R_4=H$; $R_1=R_2=R_4=H, R_3=Me, OMe$; $R_1-R_3=H, R_4=OMe$; $R_1=R_3=R_4=H, R_2=OMe$; etc.) were oxidized by $PhIO_2$ to afford a mixture of 1,2- and 1,4-naphthoquinones II and III. Similar oxidation of a tetrahydro-8-naphthol IV gives mansonone A (V) and a 1,4-quinone (VI). During oxidation $PhIO_2$ preserves intact labile structural features such as a benzylic tertiary hydroxyl group or a hydroarom. ring. |
| Databáze: | OpenAIRE |
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