Serotoninergic Synapses on the Ventral Dendrite of Mauthner Neurons (an ultrastructural study using immunogold labeling)

Autor:	E. E. Grigor’eva, L. L. Pavlik, G. Z. Mikhailova, R. Sh. Shtanchaev, I. B. Mikheeva, D. A. Moshkov
Rok vydání:	2013
Předmět:	General Neuroscience Dendrite Immunogold labelling Biology Inhibitory postsynaptic potential Serotonergic Cell biology medicine.anatomical_structure Mauthner cell medicine Excitatory postsynaptic potential Ultrastructure Active zone Neuroscience
Zdroj:	Neuroscience and Behavioral Physiology. 44:5-8
ISSN:	1573-899X 0097-0549
DOI:	10.1007/s11055-013-9865-2
Popis:	Immunogold labeling was used to identify serotoninergic synapses of the chemical and mixed types on the ventral dendrite (VD) of Mauthner neurons (MN) in goldfish. These had the characteristic feature that they contained several mitochondria in the bouton and, apart from an active zone (AZ), had an obligatory desmosome-like contact (DlC). The AZ of these synapses generally contacted unlabeled chemical crested synapses, which in turn interacted directly with the VD. These latter synapses had virtually no mitochondria and lacked a DlC, such that they could be identified as inhibitory. This “two-level” organization of excitatory serotoninergic and inhibitory synapses appears to be directly related to the reciprocal mechanism regulating the functional activity of MN via the visual apparatus.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::46d53f43ebe5ca40166a1de0273c0d3f https://doi.org/10.1007/s11055-013-9865-2 Zobrazit plný text záznamu Full text from SpringerLink