Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy
| Autor: | Eduard Tolosa, Glenda M. Halliday, Connie Marras, Joseph Jankovic, John C. Rothwell, David G. Standaert, David J. Brooks, J. W. Langston, Mark Hallett, Hagai Bergman, Günther Deuschl, W. Poewe, A. J. Stoessl, Kenneth Marek, Caroline M. Tanner, Christine Klein, Anthony E. Lang, Paolo Calabresi, Mahlon R. DeLong, Dalton James Surmeier, Anthony H.V. Schapira, Jose A. Obeso, David J. Burn, Daniela Berg, Maria Stamelou, Erwan Bezard, Christopher G. Goetz, Stanley Fahn, Serge Przedborski, C. W. Olanow, Andres M. Lozano, V. Bonifati, Stéphane Lehéricy, Mayela Rodríguez-Violante, Ronald B. Postuma, G. W. Ross, Jeffrey H. Kordower, Daniel Weintraub |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Neurology Parkinson's disease business.industry Disease progression Disease medicine.disease 03 medical and health sciences Shaking palsy 030104 developmental biology 0302 clinical medicine medicine Neurology (clinical) business Psychiatry Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Movement Disorders. 32:1264-1310 |
| ISSN: | 0885-3185 |
| DOI: | 10.1002/mds.27115 |
| Popis: | This article reviews and summarizes 200 years of Parkinson's disease. It comprises a relevant history of Dr. James Parkinson's himself and what he described accurately and what he missed from today's perspective. Parkinson's disease today is understood as a multietiological condition with uncertain etiopathogenesis. Many advances have occurred regarding pathophysiology and symptomatic treatments, but critically important issues are still pending resolution. Among the latter, the need to modify disease progression is undoubtedly a priority. In sum, this multiple-author article, prepared to commemorate the bicentenary of the shaking palsy, provides a historical state-of-the-art account of what has been achieved, the current situation, and how to progress toward resolving Parkinson's disease. © 2017 International Parkinson and Movement Disorder Society. |
| Databáze: | OpenAIRE |
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