Reaction of alcohols and amines with diacetyldihydrofluorescein (DADF): Conversion into erythrosine-derivatives on TLC-plates by ammonia and iodine vapors
| Autor: | Paam N. Sharma, Arnold Brossi |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Chemistry
Alkaloid Organic Chemistry chemistry.chemical_element Iodine Erythrosine Biochemistry Catalysis Inorganic Chemistry chemistry.chemical_compound Pigment Ammonia Colchifoline Reagent Amide visual_art Drug Discovery visual_art.visual_art_medium Organic chemistry Physical and Theoretical Chemistry |
| Zdroj: | Helvetica Chimica Acta. 67:301-304 |
| ISSN: | 1522-2675 0018-019X |
| DOI: | 10.1002/hlca.19840670136 |
| Popis: | Reaction of decetylcolchicine (2) and colchifoline (3) with diacetyldihydrofluorescein (1, DADF) afforded the corresponding amide and ester derivatives, converted on TLC-plates after exposure to ammonia and iodine vapors into red colored pigments. This reaction, also observed with DADF-derivatives of codeine, quinine and mescaline is highly sensitive. The red pigment produced from the DADF-ester (6) of colchifoline formed by te ammonia-iodine treatment is the corresponding erythrosine ester derivative. DADF emerges from these investigations as a useful reagent to detect alcohols and amines in crude mixtures and for dye labeling. |
| Databáze: | OpenAIRE |
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