Syntheses of 1-deoxynojirimycin-trehalamine-fused and -linked compounds and their biological activities

Autor:	Masao Shiozaki, Osamu Ando, Reiko Yoshiike, Osamu Ubukata, Hideyuki Haruyama
Rok vydání:	1998
Předmět:	chemistry.chemical_compound Biochemistry Chemistry Organic Chemistry Drug Discovery Degradation (geology) Trehazolin Maltase 1-Deoxynojirimycin Yeast Trehalamine
Zdroj:	Tetrahedron. 54:15167-15182
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(98)00966-1
Popis:	1-Deoxynojirimycin-trehalamine-fused and -linked compounds (10, 19a and 19b) were synthesized from 1-deoxy-2,3,4,6-tetra-O-benzylnojirimycin and trehazolamine, which was obtained from natural trehazolin as a degradation product. None of these synthetic compounds exceeded 1-deoxynojirimycin in the inhibitory activities towards rat intestinal maltase and yeast α- d -glucosidase.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::46a0bc9b89de2509e3b9e97031aaca42 https://doi.org/10.1016/s0040-4020(98)00966-1 Zobrazit plný text záznamu Full Text from ScienceDirect