Anti-Biofilm and Hemolytic Effects of Cymbopogon citratus (Dc) Stapf Essential Oil
| Autor: | Ricardo Dias de Castro, Jefferson Muniz de Lima, Ana Maria Gondim Valença, Naiana Braga da Silva, Lúcio Roberto Cançado Castellano, Alessandro Leite Cavalcanti, Marianne de Lucena Rangel |
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| Rok vydání: | 2019 |
| Předmět: |
Minimum bactericidal concentration
biology Biofilm Citral biology.organism_classification Antimicrobial Streptococcus mutans law.invention chemistry.chemical_compound Minimum inhibitory concentration chemistry law Cymbopogon citratus Pediatrics Perinatology and Child Health Food science General Dentistry Essential oil |
| Zdroj: | Pesquisa Brasileira em Odontopediatria e Clínica Integrada. 19:1-10 |
| ISSN: | 1519-0501 |
| DOI: | 10.4034/pboci.2019.191.103 |
| Popis: | Objective: To perform chemical analysis and to evaluate the anti-biofilm and hemolytic effect of the essential oil of Cymbopogon citratus . Material and Methods: Gaseous chromatography coupled to mass spectrometer was performed for chemical characterization of the essential oil. To verify the antimicrobial action, the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were determined. From MIC, MBC and MFC data, concentrations were established to verify the anti-biofilm effect and for the hemolysis test on human erythrocytes. A multispecies biofilm was developed in vitro and mouthwash applications were simulated to determine the inhibition of biofilm formation or its removal. Results. The major component of the essential oil is citral. MIC verified for Streptococcus mutans was 1mg / mL, while for Candida albicans , it was 125 μg/mL, presenting microbicidal effect for both microorganisms tested. The essential oil was able to inhibit biofilm formation (p |
| Databáze: | OpenAIRE |
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