Effect on hepatonephric organs, serum metabolites and oxidative stress in post-weaning piglets fed purified zearalenone-contaminated diets with or without Calibrin-Z
| Autor: | S. L. Johnston, Zaibin Yang, F Chi, Weiren Yang, Yuxi Wang, S J Wang, J. Broomhead, Shuzhen Jiang |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Creatinine Globulin biology Glutathione peroxidase food and beverages Malondialdehyde chemistry.chemical_compound Endocrinology Food Animals chemistry Internal medicine Toxicity medicine biology.protein Alkaline phosphatase Animal Science and Zoology Creatine kinase Cholinesterase |
| Zdroj: | Journal of Animal Physiology and Animal Nutrition. 96:1147-1156 |
| ISSN: | 0931-2439 |
| Popis: | Summary The objectives of this study were to investigate the toxicity of zearalenone (ZEA) on hepatonephric organs, serum metabolites and oxidative stress of piglets and to evaluate the efficacy of Calibrin-Z (CAZ) in preventing ZEA-induced adverse effects. The experiment was conducted for 22 days using 36 piglets weaned at 21 days of age (Landrace × Yorkshire × Duroc, 18 females and 18 males; 8.84 ± 0.21 kg average body weight). Piglets of each gender were randomly allocated to the following six dietary treatments: (i) Control (basal diet only); (ii) Control + 1 g/kg CAZ; (iii) Control + 1 mg/kg ZEA; (iv) Control + 1 mg/kg ZEA + 1 g/kg CAZ; (v) Control + 1 mg/kg ZEA + 2 g/kg CAZ; (vi) Control + 1 mg/kg ZEA + 4 g/kg CAZ. Piglets were housed and fed individually for the entire experimental period. Blood samples were taken, and piglets were killed at the end of the experiment to obtain organs for physiological assessment. Results showed that piglets fed the ZEA-contaminated diet had increased (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text