Clean three-step synthesis of 4,5-dihydro-1H-pyrazoles starting from alcohols using polymer supported reagents

Autor:	Frank Haunert, Martin H. Bolli, Berthold Hinzen, Steven V. Ley
Rok vydání:	1998
Předmět:	chemistry.chemical_compound chemistry Silylation Aldol reaction Alcohol oxidation Organic chemistry Polymer supported reagents Enol Polymer supported
Zdroj:	Journal of the Chemical Society, Perkin Transactions 1. :2235-2238
ISSN:	1364-5463 0300-922X
DOI:	10.1039/a803609h
Popis:	Nafion-TMS mediated Mukaiyama aldol reaction of silyl enol ethers with aldehydes, obtained from mild oxidation of alcohols with polymer supported perruthenate (PSP), yielded α,β-unsaturated ketones, which upon treatment with hydrazines allowed the clean synthesis of 4,5-dihydro-1H-pyrazoles.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4679d9383a593b18539c4fd861860689 https://doi.org/10.1039/a803609h Zobrazit plný text záznamu