OrthoSearch
| Autor: | Marta Mattoso, Maria Luiza Machado Campos, Vanessa Oliveira Batista, Diogo A. Tschoeke, Sérgio Manuel Serra da Cruz, Alberto M. R. Dávila, Edno Silva, Frederico Tosta, Rafael R. C. Cuadrat, Clarissa Vilela |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Computer science
business.industry InformationSystems_INFORMATIONSYSTEMSAPPLICATIONS computer.software_genre Workflow engine Workflow technology World Wide Web Interoperation ComputingMethodologies_PATTERNRECOGNITION Workflow Scripting language Orchestration (computing) Perl Software engineering business computer Workflow management system computer.programming_language |
| Zdroj: | SAC |
| DOI: | 10.1145/1363686.1363983 |
| Popis: | Managing bioinformatics experiments is challenging due to the orchestration and interoperation of tools with semantics. An effective approach for managing those experiments is through workflow management systems (WfMS). We present several WfMS features for supporting genome homology workflows and discuss relevant issues for typical genomic experiments. In our evaluation we used OrthoSearch, a real genomic pipeline originally defined as a Perl script. We modeled it as a scientific workflow and implemented it on Kepler WfMS. We show a case study detecting distant homologies on trypanomatids metabolic pathways. Our results reinforce the benefits of WfMS over script languages and point out challenges to WfMS in distributed environments. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|