how to implement alternatives to the draize eye irritation test for pesticides

Autor: C. Lamb James
Rok vydání: 1989
Předmět:
Zdroj: Journal of Toxicology: Cutaneous and Ocular Toxicology. 8:93-101
ISSN: 0731-3829
DOI: 10.3109/15569528909051492
Popis: The U.S. Environmental Protection Agency (EPA) has broad authority to require testing various types of testing under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). EPA uses that authority to ensure that sufficient data are developed on the toxicity of a pesticide. Although the statute specifies the broad principles or standards that EPA applies in deciding what data are needed, the specific test types and procedures are not spelled out in the statute (FIFRA). The general testing requirements are outlined in regulations found at 40 CFR 158. While these rules specify the general minimum toxicity testing requirements for various types of pesticide products, they also provide for liberal discretion to adjust, replace, or even waive the requirements on a case-by-case basis. The rules require testing guidelines, which are specific descriptions of the typical test, but they are not so prescriptive that they cannot be amended, replaced, or eliminated as the science progresses. The Agency...
Databáze: OpenAIRE