Congenital deafness and vestibular deficit in the dobermann

Autor:	A. C. Palmer, M. K. Wilkes
Rok vydání:	1992
Předmět:	Vestibular system medicine.medical_specialty Ataxia business.industry Hearing loss Sensory system Audiology Neuroepithelial cell Autosomal recessive trait Auditory brainstem response otorhinolaryngologic diseases Medicine sense organs medicine.symptom Abnormality Small Animals business
Zdroj:	Journal of Small Animal Practice. 33:218-224
ISSN:	1748-5827 0022-4510
Popis:	A condition characterised by the early onset of vestibular deficit and hearing loss was investigated in the dobermann breed of dog. Affected pups showed behavioural signs of head tilt, circling and ataxia and there was a total absence of vestibular response to rotation or caloric stimulation. Severe deafness, as assessed by brainstem auditory evoked response testing, was present by three weeks of age in all affected animals. The inner ears showed a progressive neuroepithelial type of cochlear degeneration with loss of the auditory sensory cells. In the vestibular system, however, there was no equivalent sensory cell loss and the only abnormal feature was the absence or abnormality of the otoconia in some of the affected animals. Pedigree analysis suggested that the condition was inherited as an autosomal recessive trait.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::464fa426810572d5f43f7fecf32b3fec https://doi.org/10.1111/j.1748-5827.1992.tb01120.x Zobrazit plný text záznamu Plný text