Derivatives of nitrosoureas in treatment of patients with neuroendocrine tumors. Clinical case of successful treatment of patient with disseminated highly differentiated neuroendocrine pancreatic tumor with severe carcinoid syndrome in fourth line of therapy

Autor:	S. G. Bagrova, A. A. Kolomeytseva, N. S. Besova, А. A. Markovich, V. A. Gorbunova, E. V. Artamonova, N. V. Lyubimova, G. S. Emelyanova, Е. I. Kovalenko
Rok vydání:	2020
Předmět:	medicine.medical_specialty Nitrosourea chemistry.chemical_compound chemistry business.industry Internal medicine medicine business Gastroenterology Toxicity profile Well differentiated
Zdroj:	Medical alphabet. :38-41
ISSN:	2078-5631
Popis:	Advanced well differentiated neuroendocrine tumors (NET) have poor sensitivity to chemotherapy. Approaches to the second and subsequent lines of treatment have not been developed to date Aranosa is a derivative of nitrosourea. it is close to streptozotocin in terms of its chemical structure, but it has a more favorable toxicity profile. Aranoza is actively studied in well differentiated NET. The drug was effective in the fourth line of treatment of the patient with NET and liver metastases.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::463d2eae8c2f1f94a1ba486bbb175a68 https://doi.org/10.33667/2078-5631-2020-20-38-41 Zobrazit plný text záznamu