Study of cholinesterases of different origin by the method of inhibitor analysis (variation of structure of phosphoryl and leaving parts of dialkoxyphosphates)

Autor: S. N. Moralev, E. V. Rozengart
Rok vydání: 2006
Předmět:
Zdroj: Journal of Evolutionary Biochemistry and Physiology. 42:515-535
ISSN: 1608-3202
0022-0930
DOI: 10.1134/s0022093006050024
Popis: Analytical review is performed of literature data on inhibitor analysis of structure of cholinesterases from different animals (vertebrates, insects, molluscs) by studying rate of their interaction with 190 dialkoxyphosphates of 54 homologous series with regularly changed structure of their phosphoryl group. The presented data are discussed from the point of view of comparative biochemistry and in the light of current concepts of structure of cholinesterase active center in animals at different levels of evolutionary development.
Databáze: OpenAIRE