Autor: |
Françoise Moreau, Guy Daculsi, Eric Aguado, Eric Goyenvalle, Serge Baroth, Pierre Layrolle |
Rok vydání: |
2008 |
Předmět: |
|
Zdroj: |
Key Engineering Materials. :583-586 |
ISSN: |
1662-9795 |
DOI: |
10.4028/www.scientific.net/kem.396-398.583 |
Popis: |
An hydrated putty was prepared by mixing submicron particles, rounded particles and granules of Biphasic Calcium Phosphate (BCP) ceramics composed of HA and β-TCP phases. The material filled entirely critical sized defects in the femoral epiphysis of NZW rabbits. After 3, 6 and 12 weeks, histology revealed that submicron particles were rapidly degraded by multinucleated TRAP-positive cells. This osteoclastic resorption stimulated bone ingrowth while the large BCP particles served as scaffold supporting bone healing by osteoconduction. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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