Inflammatory Hyperalgesia: The Role of the Prostaglandin System in the Spinal Cord

Autor: Teiji Sawa, Kiyoshi Matsumura, Megumi Fujikawa, Takae Ibuki
Rok vydání: 2012
Předmět:
Zdroj: Advances in Neuroimmune Biology. 3:197-207
ISSN: 1878-948X
Popis: Hyperalgesia is a symptom often associated with inflammation. The essential role of prostaglandins (PG) in hyper- algesia has long been known since the early 1970 s. Molecular identification of PG receptors and PG-synthesizing enzymes in the late 1980 s/early 1990 s has greatly advanced the understanding of inflammatory hyperalgesia. In this review, we provide an overview of the PG system in the spinal cord, focusing on its relevance to inflammatory hyperalgesia.
Databáze: OpenAIRE