Inflammatory Hyperalgesia: The Role of the Prostaglandin System in the Spinal Cord
Autor: | Teiji Sawa, Kiyoshi Matsumura, Megumi Fujikawa, Takae Ibuki |
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Rok vydání: | 2012 |
Předmět: | |
Zdroj: | Advances in Neuroimmune Biology. 3:197-207 |
ISSN: | 1878-948X |
Popis: | Hyperalgesia is a symptom often associated with inflammation. The essential role of prostaglandins (PG) in hyper- algesia has long been known since the early 1970 s. Molecular identification of PG receptors and PG-synthesizing enzymes in the late 1980 s/early 1990 s has greatly advanced the understanding of inflammatory hyperalgesia. In this review, we provide an overview of the PG system in the spinal cord, focusing on its relevance to inflammatory hyperalgesia. |
Databáze: | OpenAIRE |
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