Technical Report
| Autor: | P. M. Frank, R. G. Hamilton, Dennis Randall Ownby, N. F. Adkinson, H. J. Zeitz, R. E. Lindberg, I. Hrusovsky, H. A. Homburger, D. Kowalski |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Chromatography
medicine.diagnostic_test business.industry Radioallergosorbent test Biochemistry (medical) Clinical Biochemistry Skin puncture General Medicine Skin test Serum specimen respiratory tract diseases Airborne allergen Matrix (chemical analysis) immune system diseases Immunoassay Immunology otorhinolaryngologic diseases medicine Multi centre business |
| Zdroj: | cclm. 32:631-638 |
| ISSN: | 1437-4331 1434-6621 |
| DOI: | 10.1515/cclm.1994.32.8.631 |
| Popis: | ABBOTT MATRIX Aero is an enzyme immunoassay which measures specific IgE antibodies to 14 individually calibrated airborne allergens using a single serum specimen. In this study, ABBOTT MATRIX performance was evaluated in comparison to the results of skin puncture test and the Standard and Modified RAST procedures. The ABBOTT MATRIX demonstrated overall sensitivity of 89% vs. Standard RAST and Modified RAST, with specificity greater than 92% vs. both methods. ABBOTT MATRIX sensitivity vs. skin test (71%) exceeded that of the Standard and Modified RAST procedures (62% and 67% respectively). Positive results reported by ABBOTT MATRIX but not RAST were corroborated by skin test results for 3 of 5 allergens evaluated. All in vitro systems demonstrated specificity of approximately 90% vs. skin test. The ABBOTT MATRIX system provided results which compared favorably with the results of skin test and RAST, but required less hands-on time to obtain quantitative specific IgE measurements to multiple allergens. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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