Age, gender and season dependent 25(OH)D levels in children and adults living in Istanbul
| Autor: | Özlem Çakır Madenci, Özlem Hürmeydan, Asuman Orçun, Zeynep Yildiz, Nihal Yücel |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
030203 arthritis & rheumatology
0301 basic medicine business.industry Biochemistry (medical) Clinical Biochemistry Physiology medicine.disease Biochemistry vitamin D deficiency 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Vitamin D and neurology Medicine business Molecular Biology |
| Zdroj: | Turkish Journal of Biochemistry. 45:533-541 |
| ISSN: | 1303-829X 0250-4685 |
| DOI: | 10.1515/tjb-2019-0082 |
| Popis: | Background We evaluated population characteristics of serum 25-hydroxyvitamin D (25(OH)D) levels and determined the influence of age, gender and season in an extensive dataset. Materials and methods Laboratory results of 103,509 adults and 19,186 children were retrospectively evaluated. Study group was classified regarding ages as; 60 years for adults and 0–1, 1–12 months,1–3, 4–6, 7–9, 10–12, 13–15 and 16–18 years for children. Seasonal values were also determined. Levels were measured by Architect i1000 SR (Abbott Diagnostics, USA). Results The median (2.5–97.5 percentiles) of 25(OH)D levels were 38.75 (9.5–158.25) nmol/L for adults and 43.25 (11.25–125.5) nmol/L for children. There were significant gender differences for both adults and children. Values differed significantly among age subgroups (p’s Conclusion The rate of 25(OH)D deficiency was remarkable during the whole year. This will provide large-scale data about 25(OH)D status in Turkish people and may contribute to the prevention and treatment of this condition for better healthcare outcomes. |
| Databáze: | OpenAIRE |
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