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Objective: To study cognitive changes in patients with akinetic-rigid and tremor-dominant Parkinson’s disease (PD). Methods: From January to May 2019 were examined and responded 32 patients with akinetic-rigid (n=15; 46.9%) and tremor-dominant (n=17; 53.1%) PD. The average age of the patients was 66.5±3.7 years. All patients of PD before and after receiving appropriate therapy were responded using the MMSE (Mini-Mental State Examination) scale to detect the possible cognitive dysfunctions. The study of cognitive functions in patients was conducted before the start of therapy, as well as 3 months after treatment. Results: At the admission, cognitive disorders were more significant in akinetic-rigid PD than in a tremor-dominant PD. After 3 months of appropriate therapy, cognitive dysfunction rates in patients with akinetic-rigid PD improved significantly (p |