| Autor: |
N.A. Altynnik et all, A.Yu. Blinov, M.V. Medvedev |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
prenatal diagnosis. |
| Popis: |
Aberrant right subclavian artery (ARSA) is the most common embryologic abnormality of the aortic arch. 3973 fetuses were examined by ultrasound at 12–34 weeks of gestation and 34 fetuses with ARSA (mean gestational age: 20.2 weeks) was identified in our centre. ARSA was assessed in the axial plane on the level of three vessels and trachea view. ARSA was an isolated finding in 19 (55.9%) fetuses and non-isolated in 15 (44.1 %) fetuses. 6 (17.6 %) of these of 34 were aneuploidies: Trisomy 21 was diagnosed in 5 fetuses, Trisomy 18 in 1 fetus. 22q11 microdeletion was detected in 1 fetus. No cases with chromosomal abnormalities were detected in all 19 fetuses with isolated ARSA. Isolated ARSA does not seem to be associated with a significantly increased risk of aneuploidy. When ARSA is identified a detailed anatomy scan should be recommended. An invasive procedure with genetic diagnosis should be discussed when additional ultrasound abnormalities or risk factors for aneuploidy are found. Prenatal ultrasound diagnosis of ARSA based on previously published cases are discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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