Cancer anal et papillomavirus humains : une pathologie en miroir de celle du cancer du col utérin
| Autor: | J. Monsonego |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Cervical cancer
Gynecology medicine.medical_specialty Intraepithelial neoplasia education.field_of_study business.industry Incidence (epidemiology) Population Prevalence virus diseases Obstetrics and Gynecology Cancer General Medicine medicine.disease female genital diseases and pregnancy complications medicine.anatomical_structure Reproductive Medicine medicine Anal cancer business education Cervix |
| Zdroj: | Gynécologie Obstétrique & Fertilité. 38:250-254 |
| ISSN: | 1297-9589 |
| DOI: | 10.1016/j.gyobfe.2010.02.003 |
| Popis: | Anal cancer is a rare pathology in the general population but the incidence of this cancer has been on the rise for certain high-risk groups, such as homosexual men and immunodepressed subjects. The incidence of anal cancer is 10 times higher in the HIV-positive population than in the female population in general. Moderate to severe dysplasias (AIN2-3) are types of precancerous lesions that usually precede the appearance of the cancer. HPV16 infection is the most common (3/4 of the cases) followed by HPV18 (less than 10%). In anal cancer, HPV16 is present in over 75% of the cases. The prevalence of HPV in anal cancer is higher in women (90%) than in men (75%). Squamous cervical and anal cancers have strong similarities founded on the causal association to HPV, in particular HPV16. Recent data indicate that anti-HPV vaccination has a significant potential in preventing HPV infections, precancerous lesions, and anal cancer in the general population as well as in the high-risk groups. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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