Biochemical and Paraclinical Evaluation of Organ Damage in Arterial Hypertension with Associated Chronic Kidney Disease
| Autor: | Andrei Rusmir, Ioan Musta, Elena Ardeleanu, Laurentiu Sima, Teim Baaj, Ahmed Abu-Awwad, Octavian Cretu, Shamsa Baaj, Alin Adrian Cumpanas, Sebastian Plesa, Ioan Tilea, M. Botoca, Silviu Latcu, Adina Elena Protesi, Andrei Paunescu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pathology
medicine.medical_specialty Process equipment Materials Science (miscellaneous) Process Chemistry and Technology General Engineering General Chemistry General Medicine urologic and male genital diseases medicine.disease General Biochemistry Genetics and Molecular Biology Organ damage Materials Chemistry medicine General Pharmacology Toxicology and Pharmaceutics Kidney disease |
| Zdroj: | Revista de Chimie. 71:194-204 |
| ISSN: | 2668-8212 0034-7752 |
| DOI: | 10.37358/rc.20.6.8183 |
| Popis: | Organ damages, which contribute to the overall cardiovascular risk of hypertensive patients, should be early detected, prevented and treated. The study evaluated organ damage in a hypertensive study group with chronic kidney disease (CKD), compared with a study group of hypertension without CKD. Albuminuria was present in 41.2% and reduced estimated glomerular filtration rate [60 ml/min/m2 was present in 72.5% of hypertensive with CKD. The comparison of organ damage revealed in the CKD group a statistical significant higher prevalence of organ damage as follows: intima-media thickness ]0.9 mm in 39.9% vs 10.5%, carotid plaques in 28.2% vs 12.6%, left ventricular hypertrophy in 39.9% vs 31%, ankle brachial index in 6.2% vs 3.5%. Early detection and treatment of additional cardiovascular risk factors as dyslipidaemia and hyperglycaemia, that have significant role in the pathogenesis of organ damage, contribute to the better prevention of cardiovascular and renal complications in hypertension with CKD. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|