Popis: |
Purpose To evaluate the levels and differences of trace elements (Zn, Cu, Fe, Mn, Ni, Cr) in maternal-fetal systems (maternal blood, placenta, umbilical cord blood) of different healthy states. To analyze the influence of pregnancy disease on the distribution of trace elements between the mother and fetus. Methods Maternal, placental and umbilical blood samples were collected from 140 parturients (60 in the normal group, 40 in the HDCP group and 40 in the GDM group). The contents of trace elements in paired samples were determined by inductively coupled plasma–mass spectrometry (ICP–MS). SPSS software was used to analyze the differences in trace element levels in matched samples of each group. Results The distribution of Fe content in the normal group was as follows: umbilical cord blood > maternal blood > placenta (p p > 0.05). In addition, the levels of Fe in maternal blood, placental blood and umbilical cord blood in the HDCP group were higher than those in the normal control group (p umbilical cord blood > maternal blood. There were significant differences in Mn content between the placenta and maternal and umbilical cord blood (p umbilical cord blood > maternal blood. There were significant differences in the Mn content between the placenta, maternal blood and umbilical blood in the HDCP group (p p p p |