Immediate and remote effects of antitumor drug on the morphology of rat liver

Autor:	V. E. Gol’dberg, T. I. Fomina, M. V. Filipova, Gol'dberg Ed, T. V. Vetoshkina, T. Yu. Dubskaya
Rok vydání:	1998
Předmět:	Drug business.industry media_common.quotation_subject Maximum tolerated dose Rat liver Immunology Medicine CCL4 General Medicine Pharmacology business General Biochemistry Genetics and Molecular Biology media_common
Zdroj:	Bulletin of Experimental Biology and Medicine. 126:1140-1143
ISSN:	1573-8221 0007-4888
Popis:	Experiments performed on rats have shown that a single intravenous injection of the antitumor preparations platidiam and pharmorubicine in the maximum tolerated dose cause morphological changes in the liver which are preserved for 3 months after platidiam and for 6 moths after pharmorubicine. Instability of reparative processes in the liver was revealed when the rats were poisoned with CCl4, 1, 3, and 6 months after administration of the cytostatics.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4567d51285d5a807fdfea2cb241f0a84 https://doi.org/10.1007/bf02447256 Zobrazit plný text záznamu Full text from SpringerLink