Biotinylated chitosan-based SPIONs with potential in blood-contacting applications
| Autor: | Ivona Andreea Petrache, Liliana Verestiuc, John Tsibouklis, Marcel Popa, Vera Balan, Eugen Barbu, Maria Butnaru |
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| Rok vydání: | 2012 |
| Předmět: |
Materials science
Nanoparticle Ionic bonding Bioengineering Nanotechnology General Chemistry engineering.material Condensed Matter Physics Atomic and Molecular Physics and Optics Chitosan chemistry.chemical_compound chemistry Chemical engineering Biotin Coating Modeling and Simulation Biotinylation engineering Nanobiotechnology General Materials Science Magnetite |
| Zdroj: | Journal of Nanoparticle Research. 14 |
| ISSN: | 1572-896X 1388-0764 |
| Popis: | Haemocompatible biotinylated superparamagnetic nanoparticles (size range 300–700 nm) have been obtained by coating magnetite through ionic gelation with a mixture of chitosan and sodium tripolyphosphate, followed by subsequent functionalisation with biotin. The evaluations of their magnetic properties together with haemocompatibility tests have shown that these nanoparticles exhibit the prerequisite behaviour for use in magnetic field–assisted separations within biological systems. |
| Databáze: | OpenAIRE |
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