'Impact of maternal asthma on perinatal outcomes.' F. Firoozi, C. Lemiere, M-F. Beauchesne, S. Perreault, A. Forget, and L. Blais
| Autor: | Faranak Firoozi, Sylvie Perreault, Lucie Blais, M-F. Beauchesne, Catherine Lemière, A. Forget |
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| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | European Respiratory Journal. 38:1490-1490 |
| ISSN: | 1399-3003 0903-1936 |
| DOI: | 10.1183/09031936.00029109 |
| Popis: | The are conflicting results concerning the impact of maternal asthma during pregnancy on perinatal outcomes. We investigated the associations between maternal asthma during pregnancy and the risk of a small-for-gestational-age (SGA) infant, a low-birth-weight (LBW) infant, and preterm birth using a large population-based cohort. A population-based cohort of 40,788 pregnancies from asthmatic and non-asthmatic females was reconstructed through the linking of three Quebec (Canada) administrative databases between 1990 and 2002. A two-stage sampling cohort design was used to collect additional information by way of a mailed questionnaire. The generalized estimation equation models were used to obtain adjusted odds ratios of SGA, LBW and preterm birth comparing asthmatic and non-asthmatic females. The cohort included 13,007 pregnancies from asthmatic and 27,781 pregnancies from non-asthmatic females. Final estimates showed that the risk of SGA (OR: 1.27, 95% CI: 1.14–1.41), LBW (OR: 1.41, 95% CI: 1.22–1.63) and preterm delivery (OR: 1.64, 95%CI:1.46–1.83) was significantly higher among asthmatic than non-asthmatic females. Mothers with asthma during pregnancy have a higher risk of having SGA, LBW, or preterm birth infants than non-asthmatic females. However, external validity might be an issue since the cohort under represents females with high socio-economic status. |
| Databáze: | OpenAIRE |
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